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Similarly, two patients from a family with chilblain lupus associated with mutated stimulator of interferon genes treated with tofacitinib 5 mg bd displayed clinical improvement, along with suppression of the IFN signature [ 72 ], while a another case study reported a patient with the same disease successfully treated with ruxolitinib [ 73 ].

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Herein, we describe the immune-mediated rheumatological indications—other than RA—for which JAK inhibitors have been approved or tested in clinical trials.

Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis.

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Kak Viigrat V Book Of Ra
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